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Domainex is able to support its clients with biochemical assays, as a component of integrated drug discovery projects, where we are also providing medicinal or computational chemistry capabilities.
Our skilled assay biologists are able to develop and validate enzyme and ligand-binding assays in a wide-range of spectrophotometric, luminescence and fluorescence based formats. We can screen and characterise compounds in medium-throughput assays for hit-finding and later during the lead optimisation phase of your discovery programme.
We are also able to characterise compounds as they are produced using kinetic solubility, Cytochrome P450 inhibition and microsomal clearance assays, and feed this information back into our drug design.