Domainex provides high quality medicinal chemistry services that efficiently progress drug discovery projects from hit identification through lead optimization, to effective drug candidates. Our medicinal chemists have extensive experience in developing drug candidates from screening hits, which has provided us with one of the best track records in the industry, with 3 compounds entering clinical trials in the last 4 years and the selection of 2 additional compounds as pre-clinical candidates in the last 12 months.
Supported by our computational chemistry expertise, Domainex will design and provide a medicinal chemistry program tailored to your specific requirements. Our “every compound counts” philosophy means that we take into account all the relevant properties including biological activity, selectivity, pharmacokinetic (i.e. ADME) and toxicology properties, as well as patentability, in the design of your compounds.
Domainex excels in a number of drug discovery services including:-
With an established track record In target classes as diverse as:
Our medicinal chemistry services can be integrated with our computational chemistry, structural biology, protein production, DMPK and screening services to provide you with a comprehensive drug discovery strategy.
If you’d like to discover more about our services, discuss specific research, or receive a proposal, please contact us.