Call us now on: +44 (0) 1223 743170
Domainex completes successful project with UCB Pharma.
New drug discovery company Domainex and the leading global biopharmaceutical company UCB have successfully completed their first collaborative project with the creation of a particularly elusive target protein construct. Domainex used its Combinatorial Domain Hunting technology to identify a soluble and highly-expressed construct of a protein that had been refractory to other methods. This construct was then used by UCB to obtain a high-resolution crystal structure of the
target protein with a proprietary inhibitor bound to the active site.
Mark Bushfield of UCB commented: “The construct provided by Domainex has all the characteristics that we were looking for, and I am sure this would not have been found using any
other method. We are currently in discussions to agree the next stage of our collaboration".