Scientific publications and trade articles from Domainex's highly experienced team and its collaborators:
New inhibitor targeting human transcription factor HSF1: effects on the heat shock response and tumor cell survival
Vilaboa et al., (March 2017), Nucleic Acids Research
Reid J, Reich S et al., (Oct 2015), Structure
Elliott R, Ashley J et al., (Aug 2015), MedChemComm
The Discovery of a Highly Selective 5,6,7,8- Tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one SIRT2 Inhibitor that is Neuroprotective in an in vitro Parkinson’s Disease Model
Di Frusci et al., (Jan 2015), ChemMedChem
The Discovery of Potent, Selective and Reversible Inhibitors of the House Dust Mite Peptidase Allergen Der p 1: An Innovative Approach to the Treatment of Allergic Asthma
Newton G et al. (Nov 2014), J. Med. Chem.
Elizabeth H Donahue et al., (August 2014), BMC Microbiology
Lloyd Dunlap (Jun 2014), Drug Discovery News
Fanny L. Cherblanc, et al., (October 2013), J Med Chem
Nonhuman targets in allergic lung conditions
Robinson C et al., (Feb 2013), Future Medicinal Chemistry
Cirigliano J., (Sept 2012), Drug Discovery News
McCudden J., (Jun 2012), Laboratory News
Fallon P., (Jun 2012), Drug Discovery & Development
Meier C et al., (Feb 2012), J Struct Biol.
Fogl et al., (Feb 2012), Proteins
Robinson C et al., (2011), Future Med. Chem.
A combinatorial method to enable detailed investigation of protein-protein interactions
Maclagan K et al., (Mar 2011), Future Med. Chem.
Combinatorial Domain Hunting (CDH); a Novel Technique Identifies the Nature of the Interaction between NF-kB and C/EBP.
Khanjani, Shirin et al, (2011), Reproductive Sciences
Perrior T., (Fall 2010), Drug Discovery World
Littler E., (Jun 2010), Drug Discov Today
Small molecule inhibitors of the neuropilin-1 vascular endothelial growth factor A (VEGF-A) interaction
Jarvis A et al., (Mar 2010), J. Med. Chem.
(Eta-C5H4R)Fe(CO)2X], X = Cl, Br, I, NO3, CO2Me and [(eta-C5H4R)Fe(CO)3]+, R = (CH2)nCO2Me (n = 0-2), and CO2CH2CH2OH: a new group of CO-releasing molecules.
Scapens, David et al., (Nov 2007), Dalton Transactions
Combinatorial Domain Hunting: An effective approach for the identification of soluble protein domains adaptable to high-throughput applications
Reich S et al., (Oct 2006), Protein Science