Scientist at Domainex analyzing SDS PAGE gel

Scientific publications and trade articles from Domainex's highly experienced team and its collaborators:

McAlister M, et al. (2003) Method for Producing and Identifying Soluble Protein Domains. WO 03/040391

Evolving Catalytic Properties of the MLL Family SET Domain

Reid J, Reich S et al. (Oct 2015)

Design and discovery of 3-aryl-5-substituted-isoquinolin-1-ones as potent tankyrase inhibitors

Elliott R, Ashley J et al. (Aug 2015)

The Discovery of Potent, Selective and Reversible Inhibitors of the House Dust Mite Peptidase Allergen Der p 1: An Innovative Approach to the Treatment of Allergic Asthma

Newton G et al. (Nov 2014)
J. Med. Chem.

Disease-modifying treatment for COPD

Lloyd Dunlap (Jun 2014)
Drug Discovery News

Nonhuman targets in allergic lung conditions

Robinson C et al. (Feb 2013)
Future Medicinal Chemistry

Calling the X-MAN to battle cancer gene

Cirigliano J (Sept 2012)
Drug Discovery News

Putting a little structure in your drug design

McCudden J (Jun 2012)
Laboratory News

Giving Freedom of Expression to Drug Designers

Fallon P (Jun 2012)
Drug Discovery & Development

Engineering human MEK-1 for structural studies: A case study of combinatorial domain hunting

Meier C et al. (Feb 2012)
J Struct Biol. 2012 Feb;177(2):329-34

A structural and functional dissection of the cardiac stress response factor MS1

Fogl et al. (Feb 2012)
Proteins, 80(2), 398–409

Future inhaled drugs by virtual innovation: allergen delivery inhibitors

Robinson C et al. (2011)
Future Med. Chem. 3(13), 1567–1570

A combinatorial method to enable detailed investigation of protein-protein interactions

Maclagan K et al. (Mar 2011)
Future Med. Chem., 3(3), 271-282.

Overcoming Bottlenecks in drug discovery

Perrior T (Fall 2010)
Drug Discovery World, 29-33.

Combinatorial Domain Hunting: solving problems in protein expression

Littler E (Jun 2010)
Drug Discov Today. 2010 Jun;15(11-12):461-7

Small molecule inhibitors of the neuropilin-1 vascular endothelial growth factor A (VEGF-A) interaction

Jarvis A et al. (Mar 2010)
J. Med. Chem., 53(5), 2215-26.

Combinatorial Domain Hunting: An effective approach for the identification of soluble protein domains adaptable to high-throughput applications

Reich S et al. (Oct 2006)
Protein Science, 15(10), 2356–2365.