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Supporting Translational Research

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As an award winning supporter of translational research (2010 Genesis Life Science Innovation and Enterprise Programme of the Year), Domainex is committed to supporting academic groups and start-up companies to raise funding to support their drug discovery needs.

 

NEW! Apply for a Discovery STAR award here to support early academic translational research!

 

Domainex works with academics to convert their ideas and discoveries into new treatments for patients. Our in-house technologies are ideal for supporting early stage projects from hit identification and lead optimisation up to candidate selection. We have an impressive track record with three client projects entered into clinical trials and two further projects currently in preclinical studies..

Domainex currently supports a number of drug discovery consortia: for example, working with Professor Alan Ashworth’s group at Breakthrough Breast Cancer at the Institute of Cancer Research to develop a novel breast cancer drug and recently with Professor Clive Robinson’s group at St George’s University of London to invent a new treatment for asthma. In both cases, Domainex helped the groups to secure Wellcome Trust SDDI funding, and has subsequently provided medicinal and computational chemistry to facilitate their drug discovery, with the aim of nominating candidate drugs by the end of the program.

Through our extensive involvement in previous grant applications, we have built up considerable experience of the selection process used by grant administrators; such as Wellcome Trust SDDI, MRC DPFS, TSB and Biocatalyst Funds. Our teams involvement in applications that have progressed through the whole process and been funded means that we have a detailed understanding of the written guidelines and how the selection process works, as well as an excellent appreciation of what the Grant Administrators are looking for.

We can provide free advice to applicants in a number of areas and critique both preliminary and full applications, including:

  • Biological rationale of your application, and what the panel is likely to be looking for
  • How appropriate are the project objectives and milestones
  • Medicinal chemistry and Computational Chemistry program
  • Biochemical Screens and the screening cascade
  • Role and selection of external advisors
  • Organisational structure of the project and allocation of responsibilities
  • Budgets and resources – what may be deemed reasonable and necessary

We can also attend meetings and presentations with the grant administrators in order to support your application as it proceeds through the selection process.  Post-funding, Domainex looks to support the program by providing medicinal and/or computational chemistry services, and by the provision of an expert project advisor if required.

For specific case examples of where Domainex has successfully delivered on behalf of its academic collaborators, please see below:

For further information, please contact us or download a factsheet by clicking this link.