About Domainex

An Integrated Drug Discovery CRO

Domainex is a multi-award winning, integrated drug discovery CRO and has been setting the highest standards in drug discovery, with a particular emphasis on small molecule research, since 2001. We work in partnership with clients from a variety of sectors including academic, pharmaceutical, biotechnology and patient foundation organisations around the world.

Proven Track Record of Success

We offer you tailored services for every step of the drug discovery process, from expression of recombinant proteins and screening against disease targets to identify hit compounds, through the design and medicinal chemistry optimisation of hits and leads, to take these all the way to your pre-clinical drug candidates. Our multidisciplinary team of scientists works closely with you to generate innovative ideas, and to deliver high-quality results and outputs (e.g. crystallography-grade proteins and novel compounds that meet the desired target product profile), whilst at all times upholding the very highest standards of confidentiality. We have established a strong reputation with a very high level of repeat business and a proven record of success, some of which we can illustrate through the publications and case studies our clients have allowed us to put in the public domain. In 2022, >95% of our clients said they would recommend us to someone in their network. We have also received several awards recognising our customer focus and innovative approach to drug discovery.

A tailored solution for your project

We invite you to find out more about our capabilities, to get to know us and to talk to us about your requirements. We will provide you with comprehensive proposals for your consideration within a short time frame. 

We look forward to hearing from you.

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Our Vision

To be the pre-eminent partner for innovative drug discovery services that improve the quality of life for people living with disease.

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We will provide outstanding drug discovery services by deploying cutting edge technologies, building lasting relationships and continually advancing our offering.

We know that we are strongest when we work as an integrated team, and towards those ends we foster a highly collaborative, diverse company culture centred on teamwork and continual learning.

Our operations will be underpinned by innovation and passion for high quality science, while respecting wider environmental, social and governance responsibilities.

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Innovative and Customised Services

We integrate seamlessly our innovative and customised biology and chemistry services to advance your disease research projects in a timely and efficient way. Our experience spans a broad range of therapeutic areas, including oncology, inflammation, respiratory and cardiovascular diseases. We have expertise across a wide range of drug target classes, including protein-protein interactions, epigenetic targets (e.g. lysine methyltransferases), a wide range of enzymes (including kinases and proteases),ion channels, and G-protein coupled receptors (GPCRs). Whatever the research phase of your project, we have an unrivalled track record of solving complex challenges.

In addition to our small-molecule drug discovery expertise, we also support clients in other industries, such as biologics, agrochemicals and materials science.

Highly Qualified and Experienced Scientists

Ultimately what determines the success of your project are our scientists – who become committed members of your team, and an extension of your own resources. Our multi-disciplinary team of ~ 100 scientists has a wealth of experience in drug discovery – on average over 10 years per scientist. About 75% of our scientists are PhD qualified and most have previous experience gained from a variety of pharmaceutical and biotechnology companies as well as from leading academic institutes.