A leading medicinal chemistry service provider, we can efficiently progress your project from hit identification through lead generation and optimisation, to the nomination of promising drug candidates. Over 85% of our medicinal chemists have a PhD and, combined with their extensive experience in developing drug candidates against a broad range of target classes and therapeutic areas, they give you access to an unrivalled breadth of knowledge and a proven track record of successful innovation (for case studies see TBK-1/IKK, Der p1 and Tankyrase).
Every Compound Counts
Domainex chemists will provide you with a medicinal chemistry programme tailored to your specific requirements. Our “every compound counts” philosophy means that we design molecules taking into account all of the relevant properties, including biological activity, selectivity, pharmacokinetic and toxicology properties, to produce developable, patentable compounds and minimise late-stage attrition. We are able to offer you integrated teams of medicinal and computational chemists, protein, structural and assay biologists, and ADME/DMPK scientists – all working ‘under one roof’ at our Medicines Research Centre near Cambridge, UK. This means that we are able to keep the time for each “design-make-test” cycle to a minimum, so that we can progress your research programmes more quickly and efficiently.