A Robust Assay for Assessing the Effects of Compounds on the Cell Cycle

Proper functioning of the cell cycle is crucial for cell survival and replication. Cell cycle checkpoints control the progression of the cell through the different stages of interphase (G1, S and G2), determining whether to proceed with cell division based on a number of internal and external cues

Domainex has established a robust assay for assessing the effects of compounds on the cell cycle in THP-1 cells. This assay is available for routine screening. Domainex can develop the assay in further cell lines, on behalf of clients, as required.