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Case Studies

Delivering innovative science

Our highly experienced and expert scientific team has an unrivalled track record of solving research challenges, delivering successful outcomes efficiently, and therefore setting the highest possible benchmark in medicines research.

CDH Case Studies

Case studies using our patented combinatorial domain hunting (CDH) technology, which has been applied to over 60 targets in a wide range of target classes. View more

Neurotensin Receptor 1: Purification by PoLiPa

We used the neurotensin receptor 1 (NTSR1) as a proof-of-concept study to demonstrate the effectiveness of our PoLiPa GPCR purification process. View more

CD73: A structural biology case study

Domainex established biochemical and ligand-binding assays for CD73 and the expressed protein was also used successfully in X-ray crystallography studies. View more

Gram-Negative Antibiotics: A Drug Discovery Case Study

Domainex helped develop a novel class of gold(I) antibiotic, with broad spectrum antibacterial activity against the ESKAPE pathogens. View more

Confirmation of THP1 cell differentiation by flow cytometry

PBMC population identification using flow cytometry

Flow cytometry apoptosis assay in Jurkat cells

Spectral Shift Competition Assay: A robust and versatile assay to assess compound binding to a panel of kinases

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